职称

教授

联系电话

邮箱

jiazhu82@ytu.edu.cn

研究领域

功能有机分子设计与合成，主要针对卟啉、叶绿素a、BODIPY及其它含吡咯杂环衍生物进行设计合成，改善其光物理学和电化学性质，以期作为光敏剂应用于肿瘤光动力治疗（PDT）、染料敏化太阳能电池（DSSC）、离子识别或超分子组装等领域研究。

教育经历：

2000/09–2004/07，beat365官方网站，生物技术，理学学士

2004/09–2007/07，beat365官方网站，药物化学，医学硕士

2007/09–2012/02，Inje University（韩国），纳米工学，工学博士

2012/03–2013/02，Yonsei University（韩国），博士后

工作经历：

2013/03–2016/08，beat365官方网站，beat365官方网站，讲师

2016/09–至今，beat365官方网站，beat365官方网站，副教授

2016/06–至今，beat365官方网站，beat365官方网站，硕士研究生导师

2017/09–至今，beat365官方网站，beat365官方网站，有机化学教研室主任

科研项目：

（1）基于叶绿素氧化反应的β-取代D-π-A型二氢卟吩光敏染料的设计、合成与光伏性能（山东省自然科学基金），2015.07-2017.07，13.0万，主持

（2）具有电子给体-π共轭系统-电子受体（D-π-A）结构的新颖叶绿素类二氢卟吩光敏染料的分子设计、合成及其光伏性能研究（教育部留学回国人员科研启动基金），2015.05，3.5万，主持

（3）用于直接凝固注模成型工艺的氮化硅粉体表面改性方法与机理研究（国家自然科学基金），2015.01-2018.12，80万，参与

（4）功能染料、乳液及助剂的研发（企业横向），2018.10-2020.12，50.0万，主持

代表性论文：

（1）Xin Ren, Xiaodong Li, Ze Yang*, Xin Wang, Jianjiang He, Kun Wang, Jungang Yin*,Jiazhu Li*, Changshui Huang*, Tailoring Acetylenic Bonds in Graphdiyne for Advanced Lithium Storage,ACS Sustainable Chem. Eng.,2020, 8(7), 2614−2621.

（2）Zhen Zhang*, Ziqiang Qin, Wenxu Chang,Jiazhu Li*, Ruoqian Fan, Xing Wu, Rongrong Guo, Xiangqi Xie, Lanxin Zhou, Nickel-Catalyzed Decarboxylative Cyclization of Isatoic Anhydrides with Carbodiimides: Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones,Adv. Synth. Catal.,2020, 362, 2864-2869.

（3）Hongwei Wang*,†, Silong Sun*, Wenyang Ge*, Lanfei Zhao*, Bingqian Hou*, Kai Wang*, Zhongfan Lyu*, Liyang Chen, Shoushen Xu, Jun Guo, Min Li, Peisen Su, Xuefeng Li, Guiping Wang, Cunyao Bo, Xiaojian Fang, Wenwen Zhuang, Xinxin Cheng, Jianwen Wu, Luhao Dong, Wuying Chen, Wen Li, Guilian Xiao, Jinxiao Zhao, Yongchao Hao, Ying Xu, Yu Gao, Wenjing Liu, Yanhe Liu, Huayan Yin,Jiazhu Li, Xiang Li, Yan Zhao, Xiaoqian Wang, Fei Ni, Xin Ma, Anfei Li, Steven S. Xu, Guihua Bai, Eviatar Nevo, Caixia Gao, Herbert Ohm, Lingrang Kong†, Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat,Science,2020, 368, 844.

（4）Jian Wang, Xiangmin Wang, Zhong Zheng, Jihua Ma, Xu Wang, Woo Kyoung Lee, Young Key Shim, Il Yoon*, Jinchun Chen*,Jiazhu Li*, Efficient Metal-Free Synthesis of Dihydro[1,3]oxazines Assisted by Intramolecular Hydrogen Bonding,Bull. Korean Chem. Soc.,2020, 41(9), 884–887.

（5）Huiqiang Wu, Xiangmin Wang, Yang Liu, Yu Zhao, Xinyue Wang, Woo Kyoung Lee, Young Key Shim, Il Yoon*, Xinming Xu*, andJiazhu Li*, Efficient Synthesis of Long-wavelength Absorbing Cyanochlorophyll a Derivatives via Stereoselective Horner–Wadsworth–Emmons Reaction,Bull. Korean Chem. Soc.,2020, 41(5), 504-512.

（6）Yang Liu, Huiqiang Wu, Xiao Zhang, Qiang Pan, Xiangmin Wang, Wei Peng, Jungang Yin, Guizhi Li*,Jiazhu Li*, Jinjun Wang*, Regioselective reactions of methyl pyropheophorbide a with formaldehyde based on hydroxymethylation,Chem. Pap.,2018, 72, 1389-1398.

（7）Jiazhu Li*, Nailiang He, Yang Liu, Ziping Zhang, Xiao Zhang, Xueying Han, Yunyun Gai, Yongming Liu, Jungang Yin* and Jinjun Wang*, Synthesis and photophysical properties of novel pyridine fused chlorophyll a derivatives,Dyes Pigments,2017, 146, 189-198.

（8）Na Gao,Jia-Zhu Li*, Yan-Long Li, Zhen Wang, Jin-Jun Wang*, A facile synthesis of cyano-chlorins related to chlorophyll from formyl (pyro)-pheophorbide-a by a tandem transformation of the aldehyde into a nitrile group,Chin. Chem. Lett.,2016, 27(5): 789-794.

（9）Jiazhu Li, Yang Liu, Xi-Sen Xu, Yan-Long Li, Shan-Guo Zhang, Il Yoon, Young Key Shim, Jin-Jun Wang* and Jun-Gang Yin*, Highly efficient synthesis of novel methyl 13²-methylene mesopyropheophorbide a and its stereoselective Michael addition reaction,Org. Biomol. Chem.,2015, 13(7): 1992-1995.

（10）Jiazhu Li*, Xin Zhang, Yang Liu, Il Yoon, Dong-Kyoo Kim, Jun-Gang Yin, Jin-Jun Wang, Young Key Shim*, Synthesis, optical properties and preliminary in vitro photodynamic effect of pyridyl and quinoxalyl substituted chlorins,Bioorg. Med. Chem.,2015, 23(8):1684-1690.

（11）Jiazhu Li, Peng Zhang, Nan-Nan Yao, Li-Li Zhao, Jin-Jun Wang*, Young Key Shim*, Convenient peripheral aroyloxylation reactions of porphyrins and chlorophyll-a-based chlorins with benzoyl peroxide,Tetrahedron Lett., 2014, 55(5): 1086-1089.

（12）Il Yoon, Dorjnamjin Demberelnyamba,Jia Zhu Li, Young Key Shim, Ionic Liquid-Based Chlorins and Type III Mechanism of Photodynamic Therapy (PDT), inHandbooks of Porphyrin Science, eds. Karl M. Kadish, Kevin M. Smith and Roger Guilard, World Scientific Publishing Co. Pte. Ltd., Singapore,2014, Vol. 33, pp. 167-224. (Invited Chapter)

（13）Sudip Kumar Ghosh, Masatoshi Ishida,Jiazhu Li, Won-Young Cha, Vincent Lynch, Dongho Kim*, Jonathan L. Sessler*, Synthesis and anion binding studies of o-phenylene- vinylene-bridged tetrapyrrolic macrocycle as an expanded analogue of calix[4]pyrrole,Chem. Commun.,2014, 50: 3753-3756.

（14）Il Yoon, Jung Hwa Kim,Jia Zhu Li, Woo Kyoung Lee*, Young Key Shim*, Efficient photosensitization by a chlorin-polyoxometalate supramolecular complex,Inorg. Chem.,2014, 53(1): 3-5.

（15）IL Yoon,Jia Zhu Li, Young Key Shim*, Advance in Photosensitizers and Light Delivery for Photodynamic Therapy,Clin. Endosc.,2013, 46: 7-23.

（16）Jia Zhu Li, Jin Jun Wang, Il Yoon, Bing Cun Cui, Young Key Shim*, Synthesis of novel long wavelength cationic chlorins via stereoselective aldol-like condensation,Bioorg. Med. Chem. Lett.,2012, 22: 1846-1849.

（17）Jia Zhu Li, Li Li, Jung Hwa Kim, Bing Cun Cui, Jin Jun Wang and Young Key Shim*, Efficient synthesis and in vitro photodynamic anticancer study of new purpurinimide- hydrazone conjugates.J. Porphyr. Phthalocyan.,2011, 15(4): 264-270.

（18）Jia Zhu Li, Bing Cun Cui, Jin Jun Wang and Young Key Shim*, Aldol-like carbon-carbon condensation for pyridyl substituted chlorins.Bull. Korean Chem. Soc., 2011, 32(7): 2465-2468.

（19）李家柱,刘万卉,李付国,王进军,索有瑞,刘永军*,氢氧化锂存在下(焦)脱镁叶绿酸-a甲酯的空气重排反应,有机化学,2007, 27(12): 1594-1599.

授权发明专利：

获奖情况：

（1）beat365官方网站第七届青年教师教学竞赛一等奖，2017

（2）第一届“beat365官方网站教学质量奖”，2017

（3）第二届“beat365官方网站教学质量奖”，2018

（4）2019年beat365官方网站优秀本科毕业论文指导教师

（5）2020年beat365官方网站优秀本科毕业论文指导教师

已毕业研究生

3名

在读研究生

3名

对报考研究生要求

严谨、细心、有责任心、有追求

对本科生科研助理要求

年级

大一至大三年级

数量

8名/年

成绩

专业或班级前1/2

其它

应用化学专业